This keeps the work aligned with regulatory guidance while still allowing for detailed exploration of how the peptide behaves in various models
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A much higher concentrations can be obtained through intravenous administration,not possible with pills
Currently, there are several strategies for overcoming chemoresistance in cancer, including discontinuous dosing, modifying drug concentrations, combination therapy, and the use of natural products ( In this review, we aim to understand the mechanisms of chemotherapy resistance in GC and to explore the potential of TCM and its active components as chemotherapy sensitizers in reversing chemotherapy resistance and improving curative effect in GC
Koeth R, Culley M, Wang Z, Nemet I, Kirsop J, Org E, et al